{"id":36,"date":"2014-11-28T16:52:24","date_gmt":"2014-11-28T16:52:24","guid":{"rendered":"http:\/\/lab-dev.research.sickkids.ca\/brent-derry-lab\/?page_id=36"},"modified":"2026-04-07T15:05:57","modified_gmt":"2026-04-07T15:05:57","slug":"publications","status":"publish","type":"page","link":"https:\/\/lab.research.sickkids.ca\/derry\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"

<\/i><\/i><\/span>2026<\/span><\/a><\/h4><\/div>
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Sathaseevan A, Ahluwalia R, Yu B, Makhenko-Tang C, Nishimura H, Leong A, Kwan N, Derry WB. A stress-dependent post-embryonic role for the core CPA factor CFIM-1 in germline integrity.<\/a> Genetics<\/strong>.\u00a0<\/span>2026 Apr 4;232(4).<\/span><\/div>\n
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<\/i><\/i><\/span>2025<\/span><\/a><\/h4><\/div>
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Webster R, Quintana M, Yu B, Stacey F, Kafri R, and Derry WB. CDK-4 regulates nucleolar size and metabolism at the cost of late-life fitness in C. elegans.\u00a0<\/a> Heredity<\/strong>. 2025 May 18.<\/div>\n
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Eroglu M and Derry WB. Regulation of MAP Kinase signaling by the insulin-like growth factor pathway during C. elegans<\/i> vulval development.<\/a> MicroPubl Biol<\/strong>. 2025 March 21.<\/div>\n<\/div><\/div><\/div>

<\/i><\/i><\/span>2024<\/span><\/a><\/h4><\/div>
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Pan P, Zoberman M, Zhang P, Premachandran S, Bhatnagar S, Pilaka-Akella PP, Sun W, Li C, Martin C, Xu P, Zhang Z, Li R, Hung W, Tang H, MacGillivray K, Yu B, Zuo R, Pe K, Qin Z, Wang S, Li A, Derry WB, Zhen M, Saltzman AL, Calarco JA, Liu X. Robotic microinjection enables large-scale transgenic studies of Caenorhabditis elegans.<\/a> Nature Communications<\/strong>. 2024 Oct 14;15(1):8848.<\/span><\/span><\/p>\n

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Eroglu M, Zocher M, McAuley J, Webster R, Xiao MZX, Yu B, Mok C, Derry WB. <\/span>Noncanonical inheritance of phenotypic information by protein amyloids.<\/a> Nature Cell Biology<\/strong>. 2024 Oct;26(10):1712-1724.<\/p>\n

Yu-Xi<\/span>\u00a0Xiao<\/span><\/span>,\u00a0Seon Yong<\/span>\u00a0Lee<\/span><\/span>,\u00a0Magali<\/span>\u00a0Aguilera-Uribe<\/span><\/span>,\u00a0Reuben<\/span>\u00a0Samson<\/span><\/span>,\u00a0Aaron<\/span>\u00a0Au<\/span><\/span>,\u00a0Yukti<\/span>\u00a0Khanna<\/span><\/span>,\u00a0Zetao<\/span>\u00a0Liu<\/span><\/span>,\u00a0Ran<\/span>\u00a0Cheng<\/span><\/span>,\u00a0Kamaldeep<\/span>\u00a0Aulakh<\/span><\/span>,\u00a0Jiarun<\/span>\u00a0Wei<\/span><\/span>,\u00a0Adrian Granda<\/span>\u00a0Farias<\/span><\/span>,\u00a0Taylor<\/span>\u00a0Reilly<\/span><\/span>,\u00a0Andrea<\/span>\u00a0Habsid<\/span><\/span>,\u00a0Kevin R.<\/span>\u00a0Brown<\/span><\/span>,\u00a0Katherine<\/span>\u00a0Chan<\/span><\/span>,\u00a0Patricia<\/span>\u00a0Mero<\/span><\/span>,\u00a0Jie Qi<\/span>\u00a0Huang<\/span><\/span>, Maximilian<\/span>\u00a0Billmann<\/span><\/span>,\u00a0Mahfuzur<\/span>\u00a0Rahman<\/span><\/span>,\u00a0Chad<\/span>\u00a0Myers<\/span><\/span>,\u00a0Brenda J.<\/span>\u00a0Andrews<\/span><\/span>,\u00a0Ji-Young<\/span>\u00a0Youn<\/span><\/span>, Christopher M.<\/span>\u00a0Yip<\/span><\/span>,\u00a0Daniela<\/span>\u00a0Rotin<\/span><\/span>,\u00a0W. Brent<\/span>\u00a0Derry<\/span><\/span>, Julie D.<\/span>\u00a0Forman-Kay<\/span><\/span>,\u00a0Alan M.<\/span>\u00a0Moses<\/span><\/span>,\u00a0Iva<\/span>\u00a0Priti\u0161anac<\/span><\/span>,\u00a0Anne-Claude<\/span>\u00a0Gingras<\/span><\/span>, Jason<\/span>\u00a0Moffat.<\/span><\/span><\/span> TSC22D<\/em>,\u00a0WNK<\/em>\u00a0and\u00a0NRBP<\/em> gene families exhibit functional buffering and evolved with Metazoa for macromolecular crowd sensing<\/a>. Cell Reports.<\/b>\u00a0<\/span>2024 Jul 23;43(7):114417.<\/span><\/p>\n<\/div>\n

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Popiel EM, Ahluwalia R, Schuetz S, Yu B, Derry WB. MRCK-1 activates non-muscle myosin for outgrowth of a unicellular tube in Caenorhabditis elegans.<\/em><\/a> Development<\/strong>. 2024 Dec 1;151(23).\u00a0<\/span><\/div>\n<\/div>\n
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<\/i><\/i><\/span>2023<\/span><\/a><\/h4><\/div>
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FlemmingK,\u00a0<\/span>Smith E,\u00a0<\/span>Marchuk D,\u00a0<\/span>Derry WB,\u00a0<\/span>Adam MP,\u00a0<\/span><\/span>Mirzaa GM,\u00a0<\/span><\/span>Pagon RA,\u00a0<\/span><\/span>Wallace SE,\u00a0<\/span><\/span>Bean LJH,\u00a0<\/span><\/span>Gripp KW and\u00a0<\/span><\/span>Amemiya A. Familial Cerebral Cavernous Malformations.<\/a>\u00a0GeneReviews.<\/strong>\u00a0July 27, 2023.\u00a0<\/span><\/div>\n
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Derry WB.<\/span> Role of developmental pathways in disease.<\/a> FEBS J<\/strong>. 2023 Jul;290(13):3296-3299.<\/div>\n<\/div>\n
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Eroglu M, Yu B, Derry WB.<\/span> Efficient CRISPR\/Cas9 mediated large insertions using long single-stranded oligonucleotide donors in C. elegans.<\/a> FEBS J<\/strong>. 2023. Sep;290(18):4429-4439.<\/div>\n
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Urso SJ, Sathaseevan A, Brent Derry W, Lamitina T. <\/span>Regulation of the hypertonic stress response by the 3′ mRNA cleavage and polyadenylation complex.<\/a> Genetics<\/strong>. 2023 May 4;224(1)
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<\/i><\/i><\/span>2021<\/span><\/a><\/h4><\/div>
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Subramanian A.,\u00a0Hall M.,\u00a0Hou H.,\u00a0Mufteev M., Yu B.,\u00a0Yuki KE., Nishimura H.,\u00a0Sathaseevan A.,\u00a0Lant\u00a0B.,\u00a0Zhai B., Ellis J., Wilson\u00a0MD., Daugaard\u00a0M., Derry WB. Alternative polyadenylation is a determinant of oncogenic Ras function<\/a>. Science Advances<\/strong>. 2021.\u00a0Dec 17;7(51).
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Tan C.,\u00a0<\/span><\/span>Ginzberg MB.,\u00a0<\/span><\/span>Webster R.,\u00a0<\/span>Iyengar S.,\u00a0<\/span><\/span>Liu S.,\u00a0<\/span><\/span>Papadopoli D.,\u00a0<\/span><\/span>Concannon J.,\u00a0<\/span><\/span>Wang Y.,\u00a0<\/span><\/span>Auld DS.,\u00a0<\/span><\/span>Jenkins JL.,\u00a0<\/span><\/span>Rost H.,\u00a0<\/span><\/span>Topisirovic I.,\u00a0<\/span><\/span>Hilfinger A.,\u00a0<\/span><\/span>Derry WB.,\u00a0<\/span><\/span>Patel N.,\u00a0<\/span><\/span>Kafri R.\u00a0<\/span><\/span>Cell size homeostasis is maintained by CDK4-dependent activation of p38 MAPK<\/a>.\u00a0Developmental cell<\/strong>. <\/span>2021 May 17;S1534-5807(21)00399-3.<\/span><\/div>\n
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Shahzad U, Taccone MS, Kumar SA, Okura H, Krumholtz S, Ishida J, Mine C, Gouveia K, Edgar J, Smith C, Hayes M, Huang X, Derry WB, Taylor M, Rutka JT., Modeling human brain tumours in flies, worms, and zebrafish: From proof of principle to novel therapeutic targets.<\/a> Neuro Oncology<\/strong>. 2021 May 5;23(5):718-731.\u00a0<\/span>
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Derry WB.<\/span> CRISPR: development of a technology and its applications.<\/a> FEBS Journal<\/strong>. 2021 Jan;288(2):358-359.<\/div>\n<\/div><\/div><\/div>

<\/i><\/i><\/span>2020<\/span><\/a><\/h4><\/div>
Abdelilah-Seyfried S., Tournier-Lasserve E., and Brent Derry W. Blocking signalopathic events to treat Cerebral Cavernous Malformations.<\/a> Trends in Molecular Medicine<\/strong>. 2020 Sep;26(9):874-887.<\/p>\n

Popiel E, Derry WB. <\/b>Affinity Purification and Preparation of Peptides for Mass Spectrometry from C. elegans.<\/a>\u00a0<\/span>Methods in Molecular Biology<\/strong>. 2020;2152:479-485.<\/p>\n

Popiel E, Derry WB.\u00a0<\/b><\/span>Generation and Analysis of CCM Phenotypes in C. elegans.<\/a> Methods in Molecular Biology<\/strong><\/span>. 2020;2152:191-205.<\/p>\n

Subramanian A,\u00a0Hall M,\u00a0Hou H,\u00a0Mufteev M,\u00a0Yu B,\u00a0Yuki KE,\u00a0Nishimura H,\u00a0Sathaseevan A,\u00a0Lant B,\u00a0Zhai B, Ellis J, Wilson MD,\u00a0Daugaard M,\u00a0Derry WB.\u00a0<\/span>Alternative polyadenylation is a determinant of oncogenic Ras function<\/a>. bioRxiv<\/strong>\u00a02020.06.08.140145.<\/div><\/div><\/div>

<\/i><\/i><\/span>2019<\/span><\/a><\/h4><\/div>
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Tran, A.T, Chapman, E.M., Flamand, M.N., Yu, B., Krempel, S.J., Duchaine, T.F., Eroglu, M., & Derry, W.B. MiR-35 buffers apoptosis thresholds in the C. elegans germline by antagonizing both MAPK and core apoptosis pathways<\/a>. (2019)\u00a0\u00a0Cell Death & Differentiation<\/strong>,\u00a0 published online.<\/p>\n

Chapman, E.M., Lant, B., Ohashi, Y., Yu, B., Schertzberg, M., Go, C., Dogra, D., Koskim\u00e4ki, J., Girard, R., Li, Y., Fraser, A.G., Awad, I.,A., Abdelilah-Seyfried, S., Gingras, A.C., & Derry, W.B. A Conserved CCM Complex Promotes Apoptosis Non-autonomously by Regulating Zinc Homeostasis.<\/a> (2019) Nature Communications,\u00a0<\/strong>10 (1): 1791<\/p>\n

Koskim\u00e4ki J, Girard R, Li Y, Saadat L, Zeineddine HA, Lightle R, Moore T, Lyne S, Avner K, Shenkar R, Cao Y, Shi C, Polster SP, Zhang D, Carri\u00f3n-Penagos J, Romanos S, Fonseca G, Lopez-Ramirez MA, Chapman EM, Popiel E, Tang AT, Akers A, Faber P, Andrade J, Ginsberg M, Derry WB, Kahn ML, Marchuk DA, Awad IA. Comprehensive transcriptome analysis of cerebral cavernous malformation across multiple species and genotypes.<\/a>\u00a0 (2019)\u00a0JCI Insight,\u00a0<\/strong>published online.<\/p>\n<\/div><\/div><\/div>

<\/i><\/i><\/span>2018<\/span><\/a><\/h4><\/div>
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Lant, B., Pal, S., Chapman, E.M., Yu, B., Witvliet, D., Choi, S., Zhao, L., Albiges-Rizo, C., Faurobert, E. & Derry, W.B. Interrogating the\u00a0ccm-3<\/em> gene network.<\/a> (2018) Cell Reports<\/strong>, 24(11), 2857-2868<\/p>\n

Otten, C., Knox, J., Boulday, G., Eymery, M., Haniszewski, M., Neuenschwander, M., Radetzki, S., Vogt, I., H\u00e4hn, K., De Luca, C., Cardoso, C., Hamad, S., Gil, C.I., Roy, P., Albiges-Rizo, C., Faurobert, E., von Kries, J., Campillos, M., Tournier-Lasserve, E., Derry, W.B., Seyfried, S. Systematic pharmacological suppression uncovers novel molecular pathways involved in cerebral cavernous malformations.<\/a> (2018) EMBO Molecular Medicine<\/strong>, published online.<\/p>\n<\/div><\/div><\/div>

<\/i><\/i><\/span>2017<\/span><\/a><\/h4><\/div>
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Verster, A.J., Styles, E.B., Mateo, A., Derry, W.B., Andrews, B.J., Fraser, A.\u00a0Taxonomically restricted genes with essential functions frequently play roles in chromosome segregation in Caenorhabditis\u00a0elegans<\/i> and Saccharomyces\u00a0cerevisiae<\/i>.\u00a0<\/a>(2017)\u00a0G3<\/strong> (Bethesda)<\/span>. 7(10): 3337-3347.<\/p>\n

Pal, S., Lant, B., Yu, B., Tian, R., Tong, J., Krieger, J.R., Moran, M.F., Gingras, A.C., & Derry, W. B.\u00a0CCM-3 Promotes C. elegans<\/em> germline development by regulating vesicle trafficking cytokinesis and polarity.<\/a>\u00a0(2017) Current Biology<\/strong>. 27(6): 868-876.<\/p>\n<\/div><\/div><\/div>

<\/i><\/i><\/span>2016<\/span><\/a><\/h4><\/div>
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Mateo, A.R. & Derry, W. B. CEP-1 is pro-choice for reproductive health in C. elegans<\/em>.<\/a> (2016) Invited editorial, Cell Cycle<\/strong>. 15(21): 2843-2844.<\/p>\n

Derry, W.B. Chewing the fat about death with the\u00a0neighbours<\/a>. (2016) Invited editorial, Cell Death and Differentiation<\/strong>.\u00a023(7): 1097-1098.<\/p>\n

Eroglu, M. & Derry, W.B. (2016)\u00a0Your neighbours matter – non-autonomous control of apoptosis in development and disease<\/a>. Cell Death and Differentiation<\/strong>.\u00a023(7): 1110-1118.<\/p>\n

Mateo, A.R, Kessler, Z., Jolliffe, A.K., McGovern, O., Yu, B., Nicolucci, A., Yanowitz, J.L. & Derry, W.B. (2016) The p53-like protein CEP-1 is required for meiotic fidelity in C. elegans<\/em><\/a>. Current Biology<\/strong>.\u00a026(9): 1148-1158.<\/p>\n<\/div><\/div><\/div>

<\/i><\/i><\/span>2015<\/span><\/a><\/h4><\/div>
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Phanse, S., Wan, C., Borgeson, B., Tu, F., Drew, K., Clark, G., Xiong, X., Kagan, O., Kwan, J., Berzginov, A., Chessman, K., Pal, S., Cromar, G., Papoulas, O., Ni, Z., Boutz, D.R., Stoilova, S., Havugimana, P.C., Guo, X., Malty, R.H., Sarov, M., Greenblatt, J., Babu, M., Derry, W.B., Tillier, E., Wallingford, J.B., Parkinson, J., Marcotte, E.M. & Emili. A. (2015)\u00a0Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes<\/a>. Data in Brief<\/strong>. 6: 715-721.<\/p>\n

Wan C, Borgeson B, Phanse S, Tu F, Drew K, Clark G, Xiong X, Kagan O, Kwan J, Bezginov A, Chessman K, Pal S, Cromar G, Papoulas O, Ni Z, Boutz DR, Stoilova S, Havugimana PC, Guo X, Malty RH, Sarov M, Greenblatt J, Babu M, Derry WB<\/span>, R Tillier E, Wallingford JB, Parkinson J, Marcotte EM, Emili A. (2015) Panorama of ancient metazoan macromolecular complexes<\/a>. Nature<\/strong>. 525(7569): 339-344.<\/p>\n

Lant B, Yu B, Goudreault M, Holmyard D, Knight JD, Xu P, Zhao L, Chin K, Wallace E, Zhen M, Gingras AC,\u00a0Derry WB. (2015)\u00a0CCM-3\/STRIPAK promotes seamless tube extension through endocytic recycling.<\/a>\u00a0Nature Communications<\/span><\/strong>. 6: 6449.<\/p>\n<\/div><\/div><\/div>

<\/i><\/i><\/span>2014<\/span><\/a><\/h4><\/div>
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Lant, B. & Derry, W.B. (2014).\u00a0Immunostaining for markers of apoptosis in the Caenorhabditis elegans<\/em> germline<\/a>. Cold Spring Harbor Protocols.<\/strong>\u00a02014(5)<\/span> pii: pdb.prot080242.<\/p>\n

Lant, B. & Derry, W.B. (2014). Analysis of apoptosis in Caenorhabditis elegans<\/em><\/a>.\u00a0Cold Spring Harbor Protocols.<\/strong>\u00a02014(5): <\/span>pii: pdb.top070458.<\/p>\n

Lant, B. & Derry, W.B. (2014). High-throughput RNAi screening for germline apoptosis genes in Caenorhabditis elegans<\/em>.<\/a> Cold Spring Harbor Protocols.\u00a0<\/strong>2014(4): 428-434<\/span>.<\/p>\n

Lant, B. & Derry, W.B. (2014). Fluorescent visualization of germline apoptosis in living Caenorhabditis elegans<\/em>.<\/a> Cold Spring Harbor Protocols.<\/strong>\u00a02014(4): 420-427<\/span>.<\/p>\n

Lant, B. & Derry, W.B. (2014). Visualizing apoptosis in embryos and the germline of Caenorhabditis elegans<\/em>.<\/a> Cold Spring Harbor Protocols.<\/strong>\u00a02014(3): 278-283. Cover Article<\/span><\/p>\n

Lant, B. & Derry, W.B. (2014). Induction of germline apoptosis in Caenorhabditis elegans<\/em>.<\/a> Cold Spring Harbor Protocols.<\/strong>\u00a02014(3): 271-277.<\/p>\n

Baruah, A., Chang, H., Hall, M., Yuan, J., Gordon, S., Johnson, E., Shtessel, L.L., Yee, C., Hekimi, S., Derry, W.B., & Lee, S.S. (2014). CEP1, the Caenorhabditis elegans<\/em> p53 homolog, mediates opposing longevity outcomes in mitochondrial electron transport chain mutants<\/a>. PLoS Genetics.<\/strong>\u00a010(2): e1004097.<\/p>\n<\/div><\/div><\/div>

<\/i><\/i><\/span>2013<\/span><\/a><\/h4><\/div>
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Lant, B. & Derry, W.B. (2013). Methods for detection and analysis of apoptosis signalling in the C. elegans<\/em> germline<\/a>. Methods.<\/strong>\u00a061(2): 174-182.<\/p>\n

Leprivier, G., Remke, M., Dubuc, A., Rotblat, B., Kool, M., Agnihotr, S., El-Naggar, A., Yu, B., Mateo, A.R.F., Somasekharan, S., Tognon, C.E., Mathers, J., Thomas, R., Barokas, A., Bowden, M., Smith, S., Wu, X., Korshunov, A., Hielscher, T., Northcott, P.A., McCabe, M.G., Delattre, O., Gleave, M.E., Jan, E., Proud, C.G., Pfister, SM., Derry, W.B., Taylor, M.D., and Sorensen, P.H.B. (2013). The eEF2 kinase confers resistance to nutrient deprivation by blocking translation elongation<\/a>. Cell.<\/strong>\u00a0153(5): 1064-1079.<\/p>\n

Perrin, A.J., Gunda, M., Yu, B., Yen, K., Ito, S., Forster, S., Young, J., Tissenbaum, H.A. & Derry, W.B. (2013).\u00a0Noncanonical control of C. elegans<\/em> germline apoptosis by the insulin\/IGF-1 and Ras\/MAPK signaling pathways.<\/a>\u00a0Cell Death and Differentiation.<\/strong>\u00a020(1): 97-107.<\/p>\n

Jolliffe, A.K. & Derry, W.B. (2013). The p53 signaling network in mammals and worms.<\/a> Briefings in Functional Genomics.<\/strong>\u00a012(2): 129-141.<\/p>\n<\/div><\/div><\/div>

<\/i><\/i><\/span>2011<\/span><\/a><\/h4><\/div>
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Ceccarelli, D.F., Laister, R.C., Mulligan, V.K., Kean, M.J., Goudreault, M., Scott, I.C., Derry, W.B., Chakrabartty, A., Gingras, A.C. & Sicheri, F. (2011). CCM3\/PDCD10 heterodimerizes with germinal center kinase III (GCKIII) proteins using a mechanism analogous to CCM3 homodimerization.<\/a> Journal of Biological Chemistry.<\/strong>\u00a0286(28): 25056-25064.<\/p>\n

Kean,M.J., Ceccarelli, D., Goudreault, M., Sanches, M., Tate, S., Larsen, B., Gibson, L.C., Derry, W.B., Scott, I.C., Pelletier, L., Baillie, G., Sicheri, F. & Gingras, A.C. (2011). Structure-function analysis of core STRIPAK: a signalling complex implicated in golgi polarization.<\/a> Journal of Biological Chemistry.<\/strong>\u00a0286(28): 25065-25075.<\/p>\n

Ross, A.J., Li, M., Yu, B., Gao, M.X. & Derry, W.B. (2011). The EEL-1 ubiquitin ligase promotes DNA damage-induced germ cell apoptosis in C. elegans<\/em>. <\/a>Cell Death and Differentiation.<\/strong>\u00a018(7): 1140-1149.<\/p>\n<\/div><\/div><\/div>

<\/i><\/i><\/span>2010<\/span><\/a><\/h4><\/div>
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Ito, S., Greiss, S., Gartner, A. & Derry, W.B. (2010).\u00a0Cell-nonautonomous regulation of C. elegans<\/em> germ cell death by kri-1<\/em>.<\/a> Current Biology.<\/strong>\u00a020(4): 333-338.<\/p>\n<\/div><\/div><\/div>

<\/i><\/i><\/span>2008<\/span><\/a><\/h4><\/div>
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Gao, X. Liao, E., Yu, B., Wang, Y., Zhen, M. & Derry, W.B. (2008).\u00a0The SCFFSN-1 ubiquitin ligase controls CEP-1\/p53-dependent apoptosis in Caenorhabditis elegans<\/em>.<\/a> Cell Death and Differentiation.<\/strong>\u00a015(6): 1054-1062.<\/p>\n<\/div><\/div><\/div>

<\/i><\/i><\/span>2007<\/span><\/a><\/h4><\/div>
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Taylor, R.C., Brumatti, G., Ito, S., Hengartner, M.O., Derry, W.B. & Martin SJ. (2007). Establishing a blueprint for CED-3-dependent killing through identification of multiple substrates for this protease.<\/a> Journal of Biological Chemistry.<\/strong>\u00a0282(20): 15011-15021.<\/p>\n

Derry, W.B., Bierings, R., van Iersel, M. , Satkunendran, T., Reinke, V. & Rothman, J.H.\u00a0(2007). Regulation of developmental timing and germ cell proliferation in C. elegans<\/em> by the p53 gene network.<\/a>\u00a0Cell Death and Differentiation.<\/strong>\u00a014(4): 662-670.<\/p>\n

Quevedo, C., Kaplan, D.R. & Derry, W.B. (2007). AKT-1 regulates DNA-damage induced germline apoptosis in C. elegans<\/em>.<\/a> Current Biology.<\/strong>\u00a017(3): 286-292.<\/p>\n<\/div><\/div><\/div>

<\/i><\/i><\/span>2004<\/span><\/a><\/h4><\/div>
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Huyen, Y., Stavridi, E.S., Derry, W.B., Jeffrey, P., Rothman, J.H., Pavletich, N.P. & Halazonetis, T.D. (2004).\u00a0Structural differences in the DNA binding domains of human p53 and its evolutionary ancestor C. elegans<\/em> CEP-1.<\/a> Structure.<\/strong>\u00a012(7): 1237-1243.<\/p>\n

Dumontet, C., Jaffrezou, J.P., Tsuchiya, E., Duran, G.E., Chen, G., Derry, W.B., Wilson, L., Jordan, M.A., Sikic, B.I. (2004). Resistance to microtubule-targeted cytotoxins in a K562 leukemia cell variant associated with altered tubulin expression and polymerization.<\/a>\u00a0Bulletin du Cancer.<\/strong>\u00a091(5): E81-E112.<\/p>\n

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<\/i><\/i><\/span>2003<\/span><\/a><\/h4><\/div>
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Fukuyama, M, Gendreau, S.B., Derry, W.B. & Rothman, J.H. (2003). Essential embryonic roles of the CKI-1 cyclin-dependent kinase inhibitor in cell-cycle exit and morphogenesis in C. elegans<\/em>. <\/a>Developmental Biology.<\/strong>\u00a0260(1): 273-286.<\/p>\n<\/div><\/div><\/div>

<\/i><\/i><\/span>2001<\/span><\/a><\/h4><\/div>
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Derry, W.B., Putzke, A.P. & Rothman, J.H. (2001). Caenorhabditis elegans<\/em> p53: Role in apoptosis, meiosis, and stress resistance<\/a>. Science.<\/strong>\u00a0294(5542): 591-594.<\/p>\n

Sugimoto, A, Kusano, A., Hozak, R.R., Derry, W.B., Zhu, J. & Rothman, J.H. (2001). Many genomic regions are required for normal embryonic programmed cell death in Caenorhabditis elegans<\/em><\/a>.<\/em> Genetics.<\/strong>\u00a0158(1): 237-252.<\/p>\n<\/div><\/div><\/div>

<\/i><\/i><\/span>Precambrian Era<\/span><\/a><\/h4><\/div>
\n

Precambrian Era<\/a><\/p>\n<\/div><\/div><\/div><\/div><\/div>

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