{"id":96,"date":"2017-08-29T02:18:00","date_gmt":"2017-08-29T02:18:00","guid":{"rendered":"https:\/\/lab.research.sickkids.ca\/cangard\/?page_id=96"},"modified":"2025-12-16T17:44:05","modified_gmt":"2025-12-16T17:44:05","slug":"team","status":"publish","type":"page","link":"https:\/\/lab.research.sickkids.ca\/cangard\/about\/team\/","title":{"rendered":"Team"},"content":{"rendered":"

[vc_row][vc_column width=”1\/4″][vc_column_text css=””]\"\"[\/vc_column_text][\/vc_column][vc_column width=”3\/4″][vc_column_text]Gregory Costain MD, PhD
\n<\/strong>Asisstant Professor, Department of Paediatrics at the University of Toronto
\nStaff Physician, Division of Clinical and Metabolic Genetics, SickKids
\nScientist-Track Investigator, Genetics & Genome Biology Program, SickKids Research Institute<\/p>\n

Dr. Costain is a staff physician in the Division of Clinical & Metabolic Genetics at the Hospital for Sick Children (SickKids), and a Scientist-Track Investigator in Genetics & Genome Biology at the SickKids Research Institute. H received his MD\/PhD from the University of Toronto. He is a medical geneticist wo runs a specialized clinic for children with unexplained epilepsy, severe neurological impairment, and\/or medical complexity. his translational research program is focused on understanding the causes and consequences of rare variation in the human genome. his lab uses state-of-the-art genomic methods for discovery and delineation of novel genetic conditions, and to advance clinical diagnostics, preventive genetic medicine, and precision therapy development.[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column width=”1\/4″][\/vc_column][vc_column width=”3\/4″ css=”.vc_custom_1507519051216{margin-top: 30px !important;}”][\/vc_column][\/vc_row][vc_row][vc_column width=”1\/4″][vc_column_text]\"\"[\/vc_column_text][\/vc_column][vc_column width=”3\/4″][vc_column_text]Roberto Mendoza-Londono, MD, MSc, FCCMG, FRCPC
\n<\/strong>Associate Professor, Paediatrics and Molecular Genetics Departments at the University of Toronto
\nHead, Division of Clinical and Metabolic Genetics, SickKids
\nCo-Director, The Centre for Genetic Medicine.<\/p>\n

He obtained his Medical and Master’s degree in Biology with emphasis in Human Genetics degree from the Pontificia Universidad Javeriana in Bogot\u00e1, Colombia. He completed a residency in Paediatrics at the State University of New York in Brooklyn followed by a fellowship in Clinical and Metabolic Genetics at Baylor College of Medicine in Houston, Texas. He later joined the Genetics Division of The Hospital for Sick Children and University of Toronto in 2005.<\/p>\n

Dr. Mendoza has a long standing interest in the genetics of connective tissue disorders, skeletal dysplasias and inherited bone disorders. As a member of the Clinical Genetics team, he holds weekly General Genetics and Skeletal Dysplasias and Inherited Bone Disorders clinics. In addition, he runs a monthly multidisciplinary Bone Health Clinic with a team of health professionals from endocrinology, orthopaedics and physical therapy who are interested in providing the best evaluation and care to patients with connective tissue disorders. As the Medical Director of the Ehlers-Danlos clinic, he runs a monthly clinic that focuses on providing timely diagnosis, coordination of medical care, education and expertise in the treatment and management of EDS.<\/p>\n

His research interests include the identification of the genetic basis and molecular pathophysiologic mechanisms underlying common and novel genetic disorders, the delineation of the natural history and best management strategies for patients with skeletal dysplasias and inherited bone disorders, and the development of clinical practice guidelines for the evaluation and management of patients with connective tissue disorders and syndromes associated with hypermobility. His current projects include determining the diagnostic effectiveness of whole exome sequencing in patients with clinically and radiologically undiagnosed skeletal dysplasia syndromes, and comparing the diagnostic yield of clinical panel testing versus whole genome sequencing in patients with hypermobility type EDS.[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column width=”1\/4″][\/vc_column][vc_column width=”3\/4″][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

[vc_row][vc_column width=”1\/4″][vc_column_text css=””][\/vc_column_text][\/vc_column][vc_column width=”3\/4″][vc_column_text]Gregory Costain MD, PhD Asisstant Professor, Department of Paediatrics at the University of Toronto Staff Physician, Division of Clinical and Metabolic Genetics, SickKids Scientist-Track Investigator, Genetics & Genome Biology Program, SickKids Research Institute Dr. Costain is a staff physician in the Division of Clinical & Metabolic Genetics at the Hospital for Sick…<\/p>\n","protected":false},"author":4,"featured_media":0,"parent":269,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-96","page","type-page","status-publish","hentry","description-off"],"yoast_head":"\nTeam - Can-GARD<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/lab.research.sickkids.ca\/cangard\/about\/team\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Team\" \/>\n<meta property=\"og:description\" content=\"[vc_row][vc_column width=”1\/4″][vc_column_text css=””][\/vc_column_text][\/vc_column][vc_column width=”3\/4″][vc_column_text]Gregory Costain MD, PhD Asisstant Professor, Department of Paediatrics at the University of Toronto Staff Physician, Division of Clinical and Metabolic Genetics, SickKids Scientist-Track Investigator, Genetics & Genome Biology Program, SickKids Research Institute Dr. Costain is a staff physician in the Division of Clinical & Metabolic Genetics at the Hospital for Sick…\" \/>\n<meta property=\"og:url\" content=\"https:\/\/lab.research.sickkids.ca\/cangard\/about\/team\/\" \/>\n<meta property=\"og:site_name\" content=\"Can-GARD\" \/>\n<meta property=\"article:modified_time\" content=\"2025-12-16T17:44:05+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/lab.research.sickkids.ca\/cangard\/wp-content\/uploads\/sites\/62\/2021\/02\/Greg-Costain-Headshot-square-e1672872083675.png\" \/>\n\t<meta property=\"og:image:width\" content=\"850\" \/>\n\t<meta property=\"og:image:height\" content=\"881\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/lab.research.sickkids.ca\/cangard\/about\/team\/\",\"url\":\"https:\/\/lab.research.sickkids.ca\/cangard\/about\/team\/\",\"name\":\"Team - 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