{"id":716,"date":"2021-05-18T14:35:17","date_gmt":"2021-05-18T14:35:17","guid":{"rendered":"https:\/\/lab.research.sickkids.ca\/brumell\/?page_id=716"},"modified":"2024-12-30T19:31:43","modified_gmt":"2024-12-30T19:31:43","slug":"science-home","status":"publish","type":"page","link":"https:\/\/lab.research.sickkids.ca\/brumell\/","title":{"rendered":"Brumell Lab"},"content":{"rendered":"<p><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-1 fusion-flex-container fusion-parallax-fixed nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"--awb-background-position:center top;--awb-background-blend-mode:multiply;--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-padding-top:4vw;--awb-padding-bottom:4vw;--awb-padding-top-small:12vw;--awb-padding-bottom-small:12vw;--awb-margin-bottom:0px;--awb-min-height:calc( 100vh - 250px );--awb-background-color:rgba(0,0,0,0.35);--awb-background-image:url(&quot;https:\/\/lab.research.sickkids.ca\/brumell\/wp-content\/uploads\/sites\/147\/2024\/01\/Background.png&quot;);--awb-background-size:cover;--awb-flex-wrap:wrap;background-attachment:fixed;\" data-preload-img=\"https:\/\/lab.research.sickkids.ca\/brumell\/wp-content\/uploads\/sites\/147\/2024\/01\/Background.png\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-center fusion-flex-content-wrap\" style=\"max-width:1216.8px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-0 fusion_builder_column_1_1 1_1 fusion-flex-column fusion-animated\" style=\"--awb-bg-size:cover;--awb-width-large:100%;--awb-margin-top-large:0px;--awb-spacing-right-large:1.92%;--awb-margin-bottom-large:0px;--awb-spacing-left-large:1.92%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;\" data-animationType=\"fadeInUp\" data-animationDuration=\"0.8\" data-animationOffset=\"top-into-view\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-title title fusion-title-1 fusion-sep-none fusion-title-center fusion-title-text fusion-title-size-one\" style=\"--awb-text-color:var(--awb-color1);--awb-font-size:var(--awb-typography1-font-size);\"><h1 class=\"fusion-title-heading title-heading-center fusion-responsive-typography-calculated\" style=\"margin:0;text-transform:var(--awb-typography1-text-transform);font-size:1em;--fontSize:65;line-height:var(--awb-typography1-line-height);\">Brumell Lab<\/h1><\/div><div class=\"fusion-text fusion-text-1 fusion-text-no-margin\" style=\"--awb-content-alignment:center;--awb-font-size:26px;--awb-line-height:1.6;--awb-text-color:var(--awb-color1);--awb-margin-bottom:40px;\"><p>Exploring the interface between pathogens and human cell biology.<\/p>\n<\/div><\/div><\/div><\/div><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-2 fusion-flex-container has-pattern-background has-mask-background nonhundred-percent-fullwidth non-hundred-percent-height-scrolling fusion-no-medium-visibility fusion-no-large-visibility\" style=\"--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-padding-top-small:15px;--awb-padding-bottom-small:15px;--awb-min-height-small:500px;--awb-background-color-small:var(--awb-custom_color_1);--awb-flex-wrap:wrap;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-center fusion-flex-content-wrap\" style=\"max-width:1216.8px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-1 fusion_builder_column_1_1 1_1 fusion-flex-column\" style=\"--awb-bg-size:cover;--awb-width-large:100%;--awb-margin-top-large:0px;--awb-spacing-right-large:1.92%;--awb-margin-bottom-large:0px;--awb-spacing-left-large:1.92%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-title title fusion-title-2 fusion-sep-none fusion-title-text fusion-title-size-one\" style=\"--awb-text-color:var(--awb-color1);\"><h1 class=\"fusion-title-heading title-heading-left fusion-responsive-typography-calculated\" style=\"margin:0;--fontSize:65;line-height:var(--awb-typography1-line-height);\"><h1 style=\"text-align: center;\">The Brumell Lab<\/h1><\/h1><\/div><div class=\"fusion-text fusion-text-2\" style=\"--awb-text-color:var(--awb-color1);\"><p style=\"text-align: center;\">Exploring the interface between pathogens and human cell biology.<\/p>\n<\/div><\/div><\/div><\/div><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-3 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-padding-top:50px;--awb-padding-right:0px;--awb-padding-bottom:50px;--awb-padding-left:0px;--awb-margin-top:0px;--awb-margin-bottom:0px;--awb-flex-wrap:wrap;--awb-flex-wrap-medium:wrap;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-center fusion-flex-justify-content-center fusion-flex-content-wrap\" style=\"max-width:calc( 1170px + 0px );margin-left: calc(-0px \/ 2 );margin-right: calc(-0px \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-2 fusion_builder_column_1_2 1_2 fusion-flex-column\" style=\"--awb-padding-top:40px;--awb-padding-right:7%;--awb-padding-bottom:40px;--awb-padding-left:7%;--awb-padding-top-medium:60px;--awb-padding-bottom-medium:60px;--awb-padding-top-small:0px;--awb-bg-blend:overlay;--awb-bg-size:cover;--awb-width-large:50%;--awb-margin-top-large:0px;--awb-spacing-right-large:0px;--awb-margin-bottom-large:0px;--awb-spacing-left-large:0px;--awb-width-medium:100%;--awb-spacing-right-medium:0px;--awb-spacing-left-medium:0px;--awb-width-small:100%;--awb-margin-top-small:0px;--awb-spacing-right-small:0px;--awb-spacing-left-small:0px;\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-center fusion-content-layout-column\"><div class=\"fusion-title title fusion-title-3 fusion-sep-none fusion-title-text fusion-title-size-two\"><h2 class=\"fusion-title-heading title-heading-left fusion-responsive-typography-calculated\" style=\"margin:0;--fontSize:40;line-height:1.3;\">Our research<\/h2><\/div><div class=\"fusion-separator\" style=\"align-self: flex-start;margin-right:auto;margin-bottom:30px;width:100%;max-width:100px;\"><div class=\"fusion-separator-border sep-single sep-solid\" style=\"--awb-height:20px;--awb-amount:20px;border-color:var(--awb-color3);border-top-width:2px;\"><\/div><\/div><div class=\"fusion-text fusion-text-3\"><p>The Brumell Lab is working to understand how intracellular pathogens interact with their hosts to subvert cellular immunity and adapt host processes to their advantage.<\/p>\n<p>Although we primarily focus on <i>Salmonella<\/i> and <i>Listeria<\/i>, we have been recently expanding the common themes identified in these bacterial models to other pathogens including parasites such as <i>Trypanosoma<\/i>. By studying host-pathogen interactions, we are able to discover unique aspects of cell biology such as membrane dynamics, intracellular trafficking and autophagy.<\/p>\n<\/div><div class=\"fusion-separator fusion-full-width-sep\" style=\"align-self: center;margin-left: auto;margin-right: auto;margin-top:7px;width:100%;\"><\/div><div class=\"fusion-separator fusion-full-width-sep\" style=\"align-self: center;margin-left: auto;margin-right: auto;margin-bottom:20px;width:100%;\"><\/div><div ><a class=\"fusion-button button-flat fusion-button-default-size button-default fusion-button-default button-1 fusion-button-default-span fusion-button-default-type\" target=\"_self\" href=\"https:\/\/lab.research.sickkids.ca\/brumell\/research\/\"><span class=\"fusion-button-text awb-button__text awb-button__text--default\">Learn about our research<\/span><\/a><\/div><\/div><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-3 fusion_builder_column_1_2 1_2 fusion-flex-column fusion-flex-align-self-center\" style=\"--awb-padding-top-medium:20.39099999999999px;--awb-padding-bottom-medium:20.39099999999999px;--awb-padding-top-small:20px;--awb-padding-bottom-small:0px;--awb-bg-position:center center;--awb-bg-blend:overlay;--awb-bg-size:cover;--awb-width-large:50%;--awb-margin-top-large:0px;--awb-spacing-right-large:0px;--awb-margin-bottom-large:0px;--awb-spacing-left-large:0px;--awb-width-medium:100%;--awb-spacing-right-medium:0px;--awb-spacing-left-medium:0px;--awb-width-small:100%;--awb-spacing-right-small:0px;--awb-spacing-left-small:0px;\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-center fusion-content-layout-column\"><div class=\"fusion-image-element \" style=\"text-align:center;--awb-max-width:500px;--awb-caption-title-font-family:var(--h2_typography-font-family);--awb-caption-title-font-weight:var(--h2_typography-font-weight);--awb-caption-title-font-style:var(--h2_typography-font-style);--awb-caption-title-size:var(--h2_typography-font-size);--awb-caption-title-transform:var(--h2_typography-text-transform);--awb-caption-title-line-height:var(--h2_typography-line-height);--awb-caption-title-letter-spacing:var(--h2_typography-letter-spacing);\"><span class=\" fusion-imageframe imageframe-none imageframe-1 hover-type-none\"><img decoding=\"async\" width=\"751\" height=\"1103\" alt=\"Brumell lab photo on the stairs in the Research Institute.\" title=\"Group Photo 2\" src=\"https:\/\/lab.research.sickkids.ca\/brumell\/wp-content\/uploads\/sites\/147\/2023\/09\/Group-Photo-2.png\" data-orig-src=\"https:\/\/lab.research.sickkids.ca\/brumell\/wp-content\/uploads\/sites\/147\/2023\/09\/Group-Photo-2.png\" class=\"lazyload img-responsive wp-image-930\" srcset=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%27751%27%20height%3D%271103%27%20viewBox%3D%270%200%20751%201103%27%3E%3Crect%20width%3D%27751%27%20height%3D%271103%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E\" data-srcset=\"https:\/\/lab.research.sickkids.ca\/brumell\/wp-content\/uploads\/sites\/147\/2023\/09\/Group-Photo-2-200x294.png 200w, https:\/\/lab.research.sickkids.ca\/brumell\/wp-content\/uploads\/sites\/147\/2023\/09\/Group-Photo-2-400x587.png 400w, https:\/\/lab.research.sickkids.ca\/brumell\/wp-content\/uploads\/sites\/147\/2023\/09\/Group-Photo-2-600x881.png 600w, https:\/\/lab.research.sickkids.ca\/brumell\/wp-content\/uploads\/sites\/147\/2023\/09\/Group-Photo-2.png 751w\" data-sizes=\"auto\" data-orig-sizes=\"(max-width: 1024px) 100vw, (max-width: 640px) 100vw, 600px\" \/><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-4 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-padding-top:100px;--awb-padding-bottom:100px;--awb-padding-top-small:100px;--awb-padding-bottom-small:60px;--awb-margin-bottom:0px;--awb-background-color:var(--awb-custom_color_1);--awb-flex-wrap:wrap;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-center fusion-flex-justify-content-center fusion-flex-content-wrap\" style=\"max-width:1216.8px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-4 fusion_builder_column_1_1 1_1 fusion-flex-column\" style=\"--awb-bg-blend:overlay;--awb-bg-size:cover;--awb-width-large:100%;--awb-margin-top-large:0px;--awb-spacing-right-large:1.92%;--awb-margin-bottom-large:40px;--awb-spacing-left-large:1.92%;--awb-width-medium:50%;--awb-spacing-right-medium:3.84%;--awb-spacing-left-medium:3.84%;--awb-width-small:100%;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-counters-box counters-box row fusion-clearfix fusion-columns-4\" style=\"--awb-body-color:var(--awb-color1);--awb-body-size:18;--awb-border-color:var(--awb-custom_color_1);--awb-color:#ffffff;--awb-border-color:var(--awb-custom_color_1);\"><div class=\"fusion-counter-box fusion-column col-counter-box counter-box-wrapper col-lg-3 col-md-3 col-sm-3\" data-animationOffset=\"top-into-view\"><div class=\"counter-box-container\"><div class=\"content-box-percentage content-box-counter\"><span class=\"display-counter\" data-value=\"155\" data-direction=\"up\" data-decimals=\"0\">0<\/span><\/div><div class=\"counter-box-content\">Publications<\/div><\/div><\/div><div class=\"fusion-counter-box fusion-column col-counter-box counter-box-wrapper col-lg-3 col-md-3 col-sm-3\" data-animationOffset=\"top-into-view\"><div class=\"counter-box-container\"><div class=\"content-box-percentage content-box-counter\"><span class=\"display-counter\" data-value=\"29300\" data-direction=\"up\" data-decimals=\"0\">0<\/span><\/div><div class=\"counter-box-content\">Citations<\/div><\/div><\/div><div class=\"fusion-counter-box fusion-column col-counter-box counter-box-wrapper col-lg-3 col-md-3 col-sm-3\" data-animationOffset=\"top-into-view\"><div class=\"counter-box-container\"><div class=\"content-box-percentage content-box-counter\"><span class=\"display-counter\" data-value=\"41\" data-direction=\"up\" data-decimals=\"0\">0<\/span><\/div><div class=\"counter-box-content\">Alumni<\/div><\/div><\/div><div class=\"fusion-counter-box fusion-column col-counter-box counter-box-wrapper col-lg-3 col-md-3 col-sm-3\" data-animationOffset=\"top-into-view\"><div class=\"counter-box-container\"><div class=\"content-box-percentage content-box-counter\"><span class=\"display-counter\" data-value=\"736829\" data-direction=\"up\" data-decimals=\"0\">0<\/span><\/div><div class=\"counter-box-content\">Images acquired<\/div><\/div><\/div><\/div><div style=\"text-align:center;\"><a class=\"fusion-button button-flat fusion-button-default-size button-custom fusion-button-default button-2 fusion-button-default-span fusion-button-default-type\" style=\"--button_accent_color:var(--awb-color1);--button_border_color:#000000;--button_accent_hover_color:var(--awb-color1);--button_border_hover_color:var(--awb-color1);--button_gradient_top_color:var(--awb-color7);--button_gradient_bottom_color:var(--awb-color7);--button_gradient_top_color_hover:var(--awb-color4);--button_gradient_bottom_color_hover:var(--awb-color4);--button_margin-top:25px;\" target=\"_self\" href=\"https:\/\/lab.research.sickkids.ca\/brumell\/publications\/\"><span class=\"fusion-button-text awb-button__text awb-button__text--default\">Browse publications<\/span><\/a><\/div><\/div><\/div><\/div><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-5 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-padding-top:20px;--awb-padding-right:0px;--awb-padding-bottom:0px;--awb-padding-left:0px;--awb-margin-top:0px;--awb-margin-bottom:0px;--awb-background-color:var(--awb-color1);--awb-flex-wrap:wrap;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-center fusion-flex-justify-content-center fusion-flex-content-wrap\" style=\"max-width:calc( 1170px + 0px );margin-left: calc(-0px \/ 2 );margin-right: calc(-0px \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-5 fusion_builder_column_1_2 1_2 fusion-flex-column fusion-no-small-visibility\" style=\"--awb-padding-top-medium:20.39099999999999px;--awb-padding-bottom-medium:20.39099999999999px;--awb-bg-position:center center;--awb-bg-blend:overlay;--awb-bg-size:cover;--awb-width-large:50%;--awb-margin-top-large:0px;--awb-spacing-right-large:0px;--awb-margin-bottom-large:0px;--awb-spacing-left-large:0px;--awb-width-medium:100%;--awb-order-medium:1;--awb-spacing-right-medium:0px;--awb-spacing-left-medium:0px;--awb-width-small:100%;--awb-spacing-right-small:0px;--awb-spacing-left-small:0px;\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-image-element \" style=\"text-align:center;--awb-aspect-ratio:1 \/ 1;--awb-max-width:500px;--awb-caption-title-font-family:var(--h2_typography-font-family);--awb-caption-title-font-weight:var(--h2_typography-font-weight);--awb-caption-title-font-style:var(--h2_typography-font-style);--awb-caption-title-size:var(--h2_typography-font-size);--awb-caption-title-transform:var(--h2_typography-text-transform);--awb-caption-title-line-height:var(--h2_typography-line-height);--awb-caption-title-letter-spacing:var(--h2_typography-letter-spacing);\"><div style=\"display:inline-block;width:500px;\"><span class=\" fusion-imageframe imageframe-none imageframe-2 hover-type-none has-aspect-ratio\"><img decoding=\"async\" width=\"2100\" height=\"1391\" alt=\"Image of the Hospital for Sick Children&#039;s Research Institute.\" title=\"Sept 24 -2013-3 copy 3\" src=\"https:\/\/lab.research.sickkids.ca\/brumell\/wp-content\/uploads\/sites\/147\/2023\/09\/Sept-24-2013-3-copy-3.jpg\" data-orig-src=\"https:\/\/lab.research.sickkids.ca\/brumell\/wp-content\/uploads\/sites\/147\/2023\/09\/Sept-24-2013-3-copy-3.jpg\" class=\"lazyload img-responsive wp-image-883 img-with-aspect-ratio\" data-parent-fit=\"cover\" data-parent-container=\".fusion-image-element\" srcset=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%272100%27%20height%3D%271391%27%20viewBox%3D%270%200%202100%201391%27%3E%3Crect%20width%3D%272100%27%20height%3D%271391%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E\" data-srcset=\"https:\/\/lab.research.sickkids.ca\/brumell\/wp-content\/uploads\/sites\/147\/2023\/09\/Sept-24-2013-3-copy-3-200x132.jpg 200w, https:\/\/lab.research.sickkids.ca\/brumell\/wp-content\/uploads\/sites\/147\/2023\/09\/Sept-24-2013-3-copy-3-400x265.jpg 400w, https:\/\/lab.research.sickkids.ca\/brumell\/wp-content\/uploads\/sites\/147\/2023\/09\/Sept-24-2013-3-copy-3-600x397.jpg 600w, https:\/\/lab.research.sickkids.ca\/brumell\/wp-content\/uploads\/sites\/147\/2023\/09\/Sept-24-2013-3-copy-3-800x530.jpg 800w, https:\/\/lab.research.sickkids.ca\/brumell\/wp-content\/uploads\/sites\/147\/2023\/09\/Sept-24-2013-3-copy-3-1200x795.jpg 1200w, https:\/\/lab.research.sickkids.ca\/brumell\/wp-content\/uploads\/sites\/147\/2023\/09\/Sept-24-2013-3-copy-3.jpg 2100w\" data-sizes=\"auto\" data-orig-sizes=\"(max-width: 1024px) 100vw, (max-width: 640px) 100vw, 600px\" \/><\/span><\/div><\/div><\/div><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-6 fusion_builder_column_1_2 1_2 fusion-flex-column\" style=\"--awb-padding-top:20px;--awb-padding-right:6%;--awb-padding-bottom:40px;--awb-padding-left:7%;--awb-padding-top-medium:20px;--awb-padding-bottom-medium:20px;--awb-bg-blend:overlay;--awb-bg-size:cover;--awb-width-large:50%;--awb-margin-top-large:0px;--awb-spacing-right-large:0px;--awb-margin-bottom-large:0px;--awb-spacing-left-large:0px;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:0px;--awb-spacing-left-medium:0px;--awb-width-small:100%;--awb-spacing-right-small:0px;--awb-spacing-left-small:0px;\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-center fusion-content-layout-column\"><div class=\"fusion-title title fusion-title-4 fusion-sep-none fusion-title-text fusion-title-size-two\"><h2 class=\"fusion-title-heading title-heading-left fusion-responsive-typography-calculated\" style=\"margin:0;--fontSize:40;line-height:1.3;\">Research environment<\/h2><\/div><div class=\"fusion-separator\" style=\"align-self: flex-start;margin-right:auto;margin-bottom:30px;width:100%;max-width:100px;\"><div class=\"fusion-separator-border sep-single sep-solid\" style=\"--awb-height:20px;--awb-amount:20px;border-color:var(--awb-color3);border-top-width:2px;\"><\/div><\/div><div class=\"fusion-text fusion-text-4\"><p>The Brumell Lab is located in the heart of downtown Toronto at The Hospital for Sick Children (SickKids) Research Institute (RI) \u2013 one of the largest paediatric research institutes in the world. Under the RI, we have access to:<\/p>\n<\/div><ul style=\"--awb-line-height:30.6px;--awb-icon-width:30.6px;--awb-icon-height:30.6px;--awb-icon-margin:12.6px;--awb-content-margin:43.2px;\" class=\"fusion-checklist fusion-checklist-1 fusion-checklist-default type-icons\"><li class=\"fusion-li-item\" style=\"\"><span class=\"icon-wrapper circle-no\"><i class=\"fusion-li-icon fa-bacterium fas\" aria-hidden=\"true\"><\/i><\/span><div class=\"fusion-li-item-content\">World-class core facilities to support our research<\/div><\/li><li class=\"fusion-li-item\" style=\"\"><span class=\"icon-wrapper circle-no\"><i class=\"fusion-li-icon fa-bacterium fas\" aria-hidden=\"true\"><\/i><\/span><div class=\"fusion-li-item-content\">State-of-the-art light and electron microscopes<\/div><\/li><li class=\"fusion-li-item\" style=\"\"><span class=\"icon-wrapper circle-no\"><i class=\"fusion-li-icon fa-bacterium fas\" aria-hidden=\"true\"><\/i><\/span><div class=\"fusion-li-item-content\">An in-house animal facility that provides access and care for our model organisms<\/div><\/li><\/ul><div class=\"fusion-text fusion-text-5\" style=\"--awb-margin-top:15px;\"><p>We are a part of the <a href=\"https:\/\/www.sickkids.ca\/en\/research\/research-programs\/cell-systems-biology\/\" target=\"_blank\" rel=\"noopener\">Cell &amp; Systems Biology program<\/a> at SickKids, which features weekly journal clubs and seminar series with international guest speakers.<\/p>\n<\/div><div ><a class=\"fusion-button button-flat fusion-button-default-size button-default fusion-button-default button-3 fusion-button-default-span fusion-button-default-type\" target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/www.sickkids.ca\/en\/research\/about-research-institute\/\"><span class=\"fusion-button-text awb-button__text awb-button__text--default\">Learn about the RI<\/span><\/a><\/div><div class=\"fusion-separator fusion-full-width-sep\" style=\"align-self: center;margin-left: auto;margin-right: auto;margin-top:7px;width:100%;\"><\/div><div class=\"fusion-separator fusion-full-width-sep\" style=\"align-self: center;margin-left: auto;margin-right: auto;margin-bottom:20px;width:100%;\"><\/div><\/div><\/div><\/div><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-6 fusion-flex-container has-pattern-background has-mask-background nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-padding-top:50px;--awb-padding-bottom:100px;--awb-flex-wrap:wrap;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start fusion-flex-content-wrap\" style=\"max-width:1216.8px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-7 fusion_builder_column_1_1 1_1 fusion-flex-column\" style=\"--awb-bg-size:cover;--awb-width-large:100%;--awb-margin-top-large:0px;--awb-spacing-right-large:1.92%;--awb-margin-bottom-large:0px;--awb-spacing-left-large:1.92%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-title title fusion-title-5 fusion-sep-none fusion-title-center fusion-title-text fusion-title-size-two\"><h2 class=\"fusion-title-heading title-heading-center fusion-responsive-typography-calculated\" style=\"margin:0;--fontSize:40;line-height:1.3;\">Current funding<\/h2><\/div><div class=\"fusion-separator\" style=\"align-self: center;margin-left: auto;margin-right: auto;margin-bottom:30px;width:100%;max-width:100px;\"><div class=\"fusion-separator-border sep-single sep-solid\" style=\"--awb-height:20px;--awb-amount:20px;border-color:var(--awb-color3);border-top-width:2px;\"><\/div><\/div><\/div><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-8 fusion_builder_column_1_3 1_3 fusion-flex-column fusion-flex-align-self-center\" style=\"--awb-bg-size:cover;--awb-width-large:33.333333333333%;--awb-margin-top-large:0px;--awb-spacing-right-large:5.76%;--awb-margin-bottom-large:0px;--awb-spacing-left-large:5.76%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-image-element md-text-align-center sm-text-align-center\" style=\"--awb-caption-title-font-family:var(--h2_typography-font-family);--awb-caption-title-font-weight:var(--h2_typography-font-weight);--awb-caption-title-font-style:var(--h2_typography-font-style);--awb-caption-title-size:var(--h2_typography-font-size);--awb-caption-title-transform:var(--h2_typography-text-transform);--awb-caption-title-line-height:var(--h2_typography-line-height);--awb-caption-title-letter-spacing:var(--h2_typography-letter-spacing);\"><span class=\" fusion-imageframe imageframe-none imageframe-3 hover-type-none\"><img decoding=\"async\" width=\"370\" height=\"238\" alt=\"Canadian Institutes of Health Research logo\" title=\"leaf-cihr-colour-en\" src=\"https:\/\/lab.research.sickkids.ca\/brumell\/wp-content\/uploads\/sites\/147\/2023\/09\/leaf-cihr-colour-en.jpg\" data-orig-src=\"https:\/\/lab.research.sickkids.ca\/brumell\/wp-content\/uploads\/sites\/147\/2023\/09\/leaf-cihr-colour-en.jpg\" class=\"lazyload img-responsive wp-image-898\" srcset=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%27370%27%20height%3D%27238%27%20viewBox%3D%270%200%20370%20238%27%3E%3Crect%20width%3D%27370%27%20height%3D%27238%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E\" data-srcset=\"https:\/\/lab.research.sickkids.ca\/brumell\/wp-content\/uploads\/sites\/147\/2023\/09\/leaf-cihr-colour-en-200x129.jpg 200w, https:\/\/lab.research.sickkids.ca\/brumell\/wp-content\/uploads\/sites\/147\/2023\/09\/leaf-cihr-colour-en.jpg 370w\" data-sizes=\"auto\" data-orig-sizes=\"(max-width: 1024px) 100vw, (max-width: 640px) 100vw, 370px\" \/><\/span><\/div><\/div><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-9 fusion_builder_column_1_3 1_3 fusion-flex-column fusion-flex-align-self-center\" 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style=\"--awb-bg-size:cover;--awb-width-large:33.333333333333%;--awb-margin-top-large:0px;--awb-spacing-right-large:5.76%;--awb-margin-bottom-large:0px;--awb-spacing-left-large:5.76%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:0;--awb-margin-top-small:50px;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-image-element md-text-align-center sm-text-align-center\" style=\"--awb-max-width:400px;--awb-caption-title-font-family:var(--h2_typography-font-family);--awb-caption-title-font-weight:var(--h2_typography-font-weight);--awb-caption-title-font-style:var(--h2_typography-font-style);--awb-caption-title-size:var(--h2_typography-font-size);--awb-caption-title-transform:var(--h2_typography-text-transform);--awb-caption-title-line-height:var(--h2_typography-line-height);--awb-caption-title-letter-spacing:var(--h2_typography-letter-spacing);\"><span class=\" fusion-imageframe imageframe-none imageframe-5 hover-type-none\"><img decoding=\"async\" width=\"1800\" height=\"900\" alt=\"Emerging and Pandemic Infections Consortium Logo\" title=\"EPIC logo\" src=\"https:\/\/lab.research.sickkids.ca\/brumell\/wp-content\/uploads\/sites\/147\/2023\/09\/EPIC-logo.png\" data-orig-src=\"https:\/\/lab.research.sickkids.ca\/brumell\/wp-content\/uploads\/sites\/147\/2023\/09\/EPIC-logo.png\" class=\"lazyload img-responsive wp-image-938\" 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data-orig-sizes=\"(max-width: 1024px) 100vw, (max-width: 640px) 100vw, 400px\" \/><\/span><\/div><\/div><\/div><\/div><\/div><\/p>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":213,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"100-width.php","meta":{"footnotes":""},"class_list":["post-716","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.0 (Yoast SEO v27.0) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Brumell Lab - Brumell Lab<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/lab.research.sickkids.ca\/brumell\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Brumell Lab\" 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