{"id":585,"date":"2017-09-05T17:23:34","date_gmt":"2017-09-05T21:23:34","guid":{"rendered":"https:\/\/lab.research.sickkids.ca\/annie-huang\/?page_id=585"},"modified":"2024-07-16T12:30:53","modified_gmt":"2024-07-16T16:30:53","slug":"team","status":"publish","type":"page","link":"https:\/\/lab.research.sickkids.ca\/annie-huang\/team\/","title":{"rendered":"Team"},"content":{"rendered":"

[vc_row][vc_column][vc_column_text]\n\n\n\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t
\"\"<\/td>Annie Huang<\/b>
\nMD, PhD, FRCP(C)
\nPrincipal Investigator
\nAssociate Chair of Research, Department of Paediatrics, SickKids and University of Toronto
\n
\nDr Huang is a paediatric neuro-oncologist and scientist with the Cell & Systems Biology Research Program, and the Arthur and Sonia Labatt Brain Tumour Research Centre at SickKids. She holds a Tier 1 Canada Research Chair and is a Professor of Paediatrics with Medical Biophysics and Laboratory Medicine and Pathobiology at the University of Toronto.
\n
\nShe received her PhD and MD at the University of Toronto where she trained in cancer genomics and biology, and clinical oncology. Prior to starting her independent laboratory in 2005, she pursued post-doctoral training with Drs Jeremy Squire and Linda Penn at the Ontario Research Institute. She started the RBTC<\/a> to pursue her long-standing research and clinical interest in rare infant brain tumours due to the distinct clinical challenges of these patient population. In her laboratory she combines genomics, functional epigenomics and genome-wide screening tools to understand the pathogenesis of rare CNS embryonal tumours, including ATRTs (Atypical Teratoid Rhabdoid tumours), and ETMRs (Embryonal Tumour with Multi-layered Rosettes) with the goal to improve treatment and patient survival. Many of the discoveries from the Huang lab has been applied to analyses and development of clinical trials for rare tumours through her leadership in the Children\u2019s Oncology Group Trial Consortia. Due to her specific clinical and research interest\/expertise, she also frequently advises on treatment of children across the world diagnosed with rare CNS tumours.
\n
\nIn her leisure time, she enjoys historical fiction, gardening and pursuing travel and outdoor activities with her family.
\n<\/td>\n<\/tr>\n
\"\"<\/td>Mei Lu<\/b>
\nMD, PhD
\nLab Manager
\n
\nMei Lu joined Huang lab since 2010. She received her MD in Beijing, China, and her PhD in Pharmacology and Toxicology from the University of Rome, Italy. Mei is the backbone of our lab and responsible for the lab general operation and research resources (tumour bank, cell line bank and RBTC, etc.). Mei is also responsible for lab mouse work and assists various lab research projects. She assists Annie in grant management and finance. Mei still finds time for painting and fitness. In her spare time, she is also a consultant of Chinese herbal medicine.
\n
\n<\/td>\n<\/tr>\n
\"\"<\/td>Anthony Liu<\/b>
\nMD
\n
\n
\nAnthony obtained his Medical Degree with Honours from the University of Hong Kong followed by his MRCPCH (UK), MMedSc (HK), FHKAM (Paed) and FHKCPaed designations. Subsequently, he completed his fellowship training in Pediatric Neuro-Oncology at St. Jude Children\u2019s Research Hospital. Since 2021, Anthony has served as an attending Pediatric Hematologist\/Oncologist at Hong Kong Children\u2019s Hospital focusing on patients with brain and extra CNS solid tumors.
\n
\n<\/td>\n<\/tr>\n
\"\"<\/td>Liming Xu<\/b>
\nPhD
\nBioinformatician
\n
\nLiming Xu completed her PhD in Bioinformatics at Peking University in China. Since then she has worked as a bioinformatics scientist for a national research institute, a biological start-up, as well as a global company. Now she is a bioinformatician in the Huang Lab striving to understand the mechanism of paediatric tumours such as ETMR.
\n<\/td>\n<\/tr>\n
\"\"<\/td>Nikhil Raghuram<\/b>
\nMD, PhD
\nPost-Doctoral Fellow
\n
\nNikhil is currently doing his fellowship in Paediatriac Haematology\/Oncology at Sickkids. Prior to entering medical school, he did his PhD in Experimental Oncology under the guidance of Dr. Michael Hendzel's lab at the University of Alberta, Edmonton. There, he studied the role of histones and chromatin in influencing processes critical to life, such as transcription. His interests are in the field of epigenetics, and the biochemistry of tumour cells. Specifically, he is passionate about understanding the complex biology of paediatric brain tumours, given their clinical aggressiveness and the devastating effects it has on patients. It is becoming more clear that many of these tumours are driven by epigenetic modifications, leading the way for novel therapeutic interventions.
\n
\n<\/td>\n<\/tr>\n
\"\"<\/td>Oliva Palander<\/b>
\nPhD
\nPost-doc Fellow
\n
\nDr. Palander is currently doing her post-doctoral research fellowship in Paediatriac Haematology\/Oncology, Cell & Systems Biology program at Sickkids. Prior to this, she worked on primary cilia to determine how cell signaling pathways regulate diseases. She also was involved in an international research collaboration that connected a new gene mutation causing polydactyly in patients with cilia.She obtained her PhD in Biochemistry under the guidance of Dr. William Trimble at the University of Toronto, where she studied the role of formin proteins in cilia maintenance and ciliogenesis. During her MSc, she worked on retinoblastoma protein (pRB) and understanding its interaction with E2F1 in retinoblastoma. She is a biomedical scientist with a strong interest in advancing knowledge and care for rare childhood embryonal brain tumours (EBTs). Although relatively uncommon, rare EBTs comprise 40% of childhood EBTs and are frequently fatal. Current therapies are largely ineffective and unfortunately also have devastating effects on the small number of survivors. Until recently these remained neglected orphan diseases with little to no clinical or biological data. In her work at Dr. Huang\u2019s lab, she focuses on understanding molecular underpinnings of rare EBTs that develop in infants and toddlers with a specific focus on Pineoblastoma (PB), for which the Huang lab has recently uncovered a spectrum of sub-types with different molecular, clinical and survival features. Understanding the signaling pathways in PB will lay the groundwork for the discovery of novel genes and molecular circuits that are important in PB biology and in discovery of new therapeutics.
\n<\/td>\n<\/tr>\n
\"\"<\/td>Yuqing Yang <\/b>
\nM.Sc.
\nPhD Graduate Student
\nYuqing completed a Master of Science in experimental medicine from McGill University. Her work focuses on investigating the role of C19MC in embryonal tumours with multi-layered rosettes (ETMRs) heterogeneity. In her spare time, she enjoys playing jigsaw puzzles.
\n<\/td>\n<\/tr>\n
\"\"<\/td>Laurie Liu<\/b>
\nM.Sc.
\nPhD Graduate Student
\n
\nLaurie completed a Bachelor of Mathematics in statistics and computational mathematics from the University of Waterloo and a Master of Science in statistics from Queen\u2019s University. Laurie\u2019s work focuses on discovering biomarkers for high-risk embryonal brain tumours (EBTs) and developing statistical models to predict EBT patient outcome. In his own time, Laurie enjoys eating and travelling.
\n
\n<\/td>\n<\/tr>\n
\"\"<\/td>Fupan Yao<\/b>
\nPhD Graduate Student
\n
\nFupan completed a bachelor of computer science with a focus on computational biology and bioinformatics. Fupan focuses on deeper characterizations of Atypical Teratoid Rhabdoid Tumours (ATRTs) through the application of high resolution single cell RNA sequencing and multi-omics analysis. In his free time he plays too much video games and eats way too many snacks.
\n
\n<\/td>\n<\/tr>\n
\"\"<\/td>Lydia Leung<\/b>
\nMsc Graduate Student
\n
\nLydia completed a bachelor of science in life sciences from McMaster University. As a co-op student Huang lab, Lydia assisted in the coordination of the RBTC, including liaison with collaborators, maintaining the clinical database, and organization of the biobank. Currently, her graduate project focuses on evaluating the survival, toxicity and relapse patterns for patients treated by the SickKids' radiation-sparing regimen for ATRTs, as well as investigating the value of serial cerebrospinal fluid (CSF) profiling in predicting therapy resistance and early relapse in these patients.
\n
\n<\/td>\n<\/tr>\n
\"\"<\/td> Jack Reilly <\/b>
\nM.Sc
\nClinical Research Project Coordinator
\n
\nJack graduated from the University of Western Ontario with a Masters degree in Pathology and Lab Medicine. During his masters Jack focused on the diagnosis of rare neurodevelopmental disorders using DNA methylation biomarkers.
\n
\nJack now acts as our Clinical Research Project Coordinator, involved in sample collection and curation, collaborator and social outreach, and research ethics administration. <\/td>\n<\/tr>\n
<\/td><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text]<\/p>\n

Previous Members <\/p>\n
<\/div>\n<\/h3>\n

[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column][vc_tta_accordion active_section=”99″ collapsible_all=”true”][vc_tta_section title=”Students” tab_id=”1594670173769-68502dfe-ce53″][vc_column_text]Iqra Mumal, PhD, Regeneron Pharmaceuticals, Inc., New York, USA<\/p>\n

Sara Khan, PhD, MD, Nationwide Children’s Hospital, Ohio, USA<\/p>\n

Dean Popovski, PhD, MD Candidate, Melbourne Medical School, Australia<\/p>\n

Elizabeth Richardson, MSc, Medical Student<\/p>\n

Jonathan Torchia, PhD, Boston, New York, USA<\/p>\n

Patrick Sin-Chan, PhD, Regeneron Pharmaceuticals, Inc., New York, USA<\/p>\n

Tannu Suwal, MSc, San Diego, California, USA<\/p>\n

Brian Golbourn, PhD, Sammer’s Lab, USA<\/p>\n

Tara Spence, PhD, PMP, Medical Cytogeneticist and Molecular Geneticist, BC, Canada<\/p>\n

Tiffany Chan, PhD<\/p>\n

Daniel Picard, MSc, DKTK, Dusseldorf, Germany<\/p>\n

David Shih, MSc, PhD, University of Texas Health Sciences Center, Houston, Texas<\/p>\n

Kyle Lee, PhD<\/p>\n

Neilket Patel, DDS<\/p>\n

Gibran Edun<\/p>\n

Olivia Lopes<\/p>\n

Neil Chang<\/p>\n

Adil Abdullahi<\/p>\n

Alice Ma<\/p>\n

Valerie Yau<\/p>\n

Ayda Alizadeh\u00a0<\/em><\/p>\n

Shivani Kamdar<\/p>\n

Gassam Al-Awad<\/p>\n

Angela Li<\/p>\n

David Panizza, MD<\/p>\n

Paul Su<\/p>\n

Mohammed Ahmed<\/p>\n

Natalia Pikor<\/p>\n

Yaqi Hu<\/p>\n

Amy Fang<\/p>\n

Victoria Ngo<\/p>\n

Angela Chan<\/p>\n

Charles Chen<\/p>\n

Sabrina Ge<\/p>\n

Johnny Nguyen<\/p>\n

Yaqi Hu[\/vc_column_text][\/vc_tta_section][vc_tta_section title=”Post-Graduate Fellows” tab_id=”1594670228850-17e29ada-8845″][vc_column_text]Dr. Sivan Gershanov, PhD<\/p>\n

Dr. Dean Popovski, PhD<\/p>\n

Dr. Adriana Fonseca, MD<\/p>\n

Dr. Palma Solano Paez, MD<\/p>\n

Dr. Joseph Norman, PhD<\/p>\n

Dr. Alexandre Vasiljevic, MD\/PhD<\/p>\n

Dr. Cathy Lee, PhD<\/p>\n

Dr. Dennis Ku, MD<\/p>\n

Dr. John You, MD PhD<\/p>\n

Dr. Deena Gendoo, PhD<\/p>\n

Dr. Nina Hoss, MD<\/p>\n

Dr. E. Lee, MD<\/p>\n

Dr. Li Mei Zhou, PhD<\/p>\n

Dr. Yun Tao Lu, MD PhD<\/p>\n

Dr. Mei Hua Li, PhD[\/vc_column_text][\/vc_tta_section][vc_tta_section title=”Staff” tab_id=”1640814756733-b32ce8c9-224a”][vc_column_text]Poly Ho, MSc, Lawyer<\/p>\n

Natalia Ruiz, MSc, Medical student (Poland)<\/p>\n

Xiaolian Fan, PhD<\/p>\n

Salma Al-Karmi, PhD[\/vc_column_text][\/vc_tta_section][\/vc_tta_accordion][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

[vc_row][vc_column][vc_column_text][\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text] Previous Members [\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column][vc_tta_accordion active_section=”99″ collapsible_all=”true”][vc_tta_section title=”Students” tab_id=”1594670173769-68502dfe-ce53″][vc_column_text]Iqra Mumal, PhD, Regeneron Pharmaceuticals, Inc., New York, USA Sara Khan, PhD, MD, Nationwide Children’s Hospital, Ohio, USA Dean Popovski, PhD, MD Candidate, Melbourne Medical School, Australia Elizabeth Richardson, MSc, Medical Student Jonathan Torchia, PhD, Boston, New York, USA Patrick Sin-Chan, PhD, Regeneron Pharmaceuticals, Inc., New York, USA…<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-585","page","type-page","status-publish","hentry","description-off"],"yoast_head":"\nTeam - Annie Huang Lab<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/lab.research.sickkids.ca\/annie-huang\/team\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Team\" \/>\n<meta property=\"og:description\" content=\"[vc_row][vc_column][vc_column_text][\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text] Previous Members [\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column][vc_tta_accordion active_section=”99″ collapsible_all=”true”][vc_tta_section title=”Students” tab_id=”1594670173769-68502dfe-ce53″][vc_column_text]Iqra Mumal, PhD, Regeneron Pharmaceuticals, Inc., New York, USA Sara Khan, PhD, MD, Nationwide Children’s Hospital, Ohio, USA Dean Popovski, PhD, MD Candidate, Melbourne Medical School, Australia Elizabeth Richardson, MSc, Medical Student Jonathan Torchia, PhD, Boston, New York, USA Patrick Sin-Chan, PhD, Regeneron Pharmaceuticals, Inc., New York, USA…\" \/>\n<meta property=\"og:url\" content=\"https:\/\/lab.research.sickkids.ca\/annie-huang\/team\/\" \/>\n<meta property=\"og:site_name\" content=\"Annie Huang Lab\" \/>\n<meta property=\"article:modified_time\" content=\"2024-07-16T16:30:53+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/lab.research.sickkids.ca\/annie-huang\/team\/\",\"url\":\"https:\/\/lab.research.sickkids.ca\/annie-huang\/team\/\",\"name\":\"Team - 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