Research Publications from the Pearson Lab

Yorkie is required to restrict the injury responses in planarians.

Lin AYT, Pearson BJ.
PLoS Genetics. 2017; 13(7):e1006874.

A Brain Unfixed: Unlimited Neurogenesis and Regeneration of the Adult Planarian Nervous System.

Brown DDR, Pearson BJ.
Frontiers in Neuroscience. 2017; 11:289.

Nervous system development and regeneration in freshwater planarians.

Ross KG, Currie KW, Pearson BJ, Zayas RM.
Wiley interdisciplinary reviews. Developmental Biology. 2017; 6(3).


(Neo)blast from the past: new insights into planarian stem cell lineages.

Zhu SJ, Pearson BJ.
Current Opinion in Genetics & Development. 2016; 40:74-80.

Light-induced depigmentation in planarians models the pathophysiology of acute porphyrias.

Stubenhaus BM, Dustin JP, Neverett ER, Beaudry MS, Nadeau LE, Burk-McCoy E, He X, Pearson BJ, Pellettieri J.
eLife. 2016; 5.

HOX gene complement and expression in the planarian Schmidtea mediterranea.

Currie KW, Brown DD, Zhu S, Xu C, Voisin V, Bader GD, Pearson BJ.
EvoDevo. 2016; 7:7.


Mex3-1 manuscript image

A mex3 homolog is required for differentiation during planarian stem cell lineage development.

Zhu SJ, Hallows SE, Currie KW, Xu C, Pearson BJ.
eLife. 2015 Jun 26;4.

An in vivo requirement for the mediator subunit med14 in the maintenance of stem cell populations.

Burrows JT, Pearson BJ, Scott IC.
Stem Cell Reports. 2015 Apr 14;4(4):670-84.


Comparative manuscript image

A comparative transcriptomic analysis reveals conserved features of stem cell pluripotency in planarians and mammals.
Labbé RM, Irimia M, Currie KW, Lin A, Zhu SJ, Brown DD, Ross EJ, Voisin V, Bader GD, Blencowe BJ, Pearson BJ.
Stem Cells. 2012 Aug;30(8):1734-45.

Proteomic profiling of the planarian Schmidtea mediterranea and its mucous reveals similarities with human secretions and those predicted for parasitic flatworms.
Bocchinfuso DG, Taylor P, Ross E, Ignatchenko A, Ignatchenko V, Kislinger T, Pearson BJ, Moran MF.
Mol Cell Proteomics. 2012 Sep;11(9):681-91.

TORC1 is required to balance cell proliferation and cell death in planarians.
Tu KC, Pearson BJ, Sánchez Alvarado A.
Dev Biol. 2012 May 15;365(2):458-69.

A planarian p53 homolog regulates proliferation and self-renewal in adult stem cell lineages.
Pearson BJ, Sánchez Alvarado A.
Development. 2010 Jan;137(2):213-21.

Formaldehyde-based whole-mount in situ hybridization method for planarians.
Pearson BJ, Eisenhoffer GT, Gurley KA, Rink JC, Miller DE, Sánchez Alvarado A.
Dev Dyn. 2009 Feb;238(2):443-50.


Planarian PTEN homologs regulate stem cells and regeneration through TOR signaling.
Oviedo NJ, Pearson BJ, Levin M, Sánchez Alvarado A.
Dis Model Mech. 2008 Sep-Oct;1(2-3):131-43.

Regeneration, stem cells, and the evolution of tumor suppression.
Pearson BJ, Sánchez Alvarado A.
Cold Spring Harbor symposia on quantitative biology. 2008; 73:565-72.


Hhip regulates zebrafish muscle development by both sequestering Hedgehog and modulating localization of Smoothened.
Ochi H, Pearson BJ, Chuang PT, Hammerschmidt M, Westerfield M.
Dev Biol. 2006 Sep 1;297(1):127-40.

Regulation of temporal identity transitions in Drosophila neuroblasts.
Grosskortenhaus R, Pearson BJ, Marusich A, Doe CQ.
Dev Cell. 2005 Feb;8(2):193-202.


Specification of temporal identity in the developing nervous system.
Pearson BJ, Doe CQ.
Annu Rev Cell Dev Biol. 2004;20:619-47. Review.

Winkfein RJ, Pearson B, Ward R, Szerencsei RT, Colley NJ, Schnetkamp PP.
Cell Calcium. 2004 Aug;36(2):147-55.


Pearson BJ, Doe CQ.
Nature. 2003 Oct 9;425(6958):624-8.


Webel R, Haug-Collet K, Pearson B, Szerencsei RT, Winkfein RJ, Schnetkamp PP, Colley NJ.
Annals of the New York Academy of Sciences. 2002; 976:300-14.


Pierce-Shimomura JT, Faumont S, Gaston MR, Pearson BJ, Lockery SR.
Nature. 2001; 410(6829):694-8.


Haug-Collet K, Pearson B, Webel R, Szerencsei RT, Winkfein RJ, Schnetkamp PP, Colley NJ.
The Journal of Cell Biology. 1999; 147(3):659-70.

Keys DN, Lewis DL, Selegue JE, Pearson BJ, Goodrich LV, Johnson RL, Gates J, Scott MP, Carroll SB
Science. 1999 Jan 22;283(5401):532-4

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